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Author information: Patients with gender dysphoria are offered cross-sex hormone therapy rtanssexuals sex reassignment surgery to achieve the transition between the sex assigned at birth and gender identity. According to international guidelines, cross-sex hormone therapy in trans-women should lead to a psychologically and physiologically healthy body with feminized male to female transsexuals hormone levels, resulting in suppression of spermatogenesis.

However, in a recently published multi-center study, we discovered a high proportion of patients a home with a Berkeley woman male serum hormone levels and qualitatively intact spermatogenesis on the day of sex reassignment surgery. The objective of this tto was male to female transsexuals review the content of 11 publications that focus on the influence of cross-sex hormone therapy on testicular morphology.

Whereas three publications transsexuale a marked reduction of the spermatogenic level in all patients examined, eight publications reported inconsistent results. Explanations for these heterogeneous findings include insufficient cross-sex hormone therapy regarding dosage or duration.

As complete spermatogenesis is associated with virilized serum hormone levels, these patients may face challenges especially after sex reassignment surgery in frmale to the abruptly established hypogonadal state following removal of the testes. There is a need for more individualized and male to female transsexuals cross-sex hormone therapy and post-treatment regimens. Evidence-based guidelines for attending clinicians need to be established in order to deliver the most appropriate hello cupid online dating.